Register information Patent

WO file number: PCT/EP2024/062101 (Status: pending/in force, Query started: September 20, 2025)

Please note: This English version is a non-binding translation of the German register excerpt. Only the German version of the register excerpt is legally binding.

Master data
INID	Criterion	Field	Content
	Type of IP right	SART	Patent
	Status	ST	Pending/in force
86	WO file number	WAKZ	PCT/EP2024/062101
87	WO publication number	WPN	2024227868
54	Designation/title	TI	SELF-ASSEMBLING PEPTIDE AMPHIPHILES AS RETROVIRAL TRANSDUCTION ENHANCERS
51	IPC main class	ICM (ICMV)	C12N 15/87 (2006.01)
51	IPC secondary class(es)	ICS (ICSV)	A61K 31/00 (2006.01), B82Y 5/00 (2011.01), C07K 7/00 (2006.01), A61K 47/00 (2006.01), C07K 7/06 (2006.01), C07K 7/08 (2006.01)
86	WO application date	WAT	May 2, 2024
72	Inventor	IN	Inventor not yet named
33 31 32	Foreign priority	PRC PRNA PRDA	EP 23206284.4 Oct 27, 2023
33 31 32	Foreign priority	PRC PRNA PRDA	EP 23171438.7 May 3, 2023
33 31 32	Foreign priority	PRC PRNA PRDA	EP 23171437.9 May 3, 2023
	Patent division in charge		13
87	WO language of publication	WLANG	EN - Englisch
57	Abstract	AB	The present invention relates to self-assembling peptide amphiphiles consisting of a non-self-assembling peptide moiety having a positive net charge under physiological pH, and a hydrophobic moiety covalently coupled to the peptide moiety, wherein the peptide moiety is composed of a positively charged peptide part and a β-sheet forming peptide part, wherein the hydrophobic moiety is covalently coupled to the β-sheet forming peptide part, wherein the peptide amphiphiles self-assemble into fibrils and form μm-sized aggregates in aqueous medium, and wherein the fibrils are efficiently degradable in cells. The peptide amphiphiles of the present invention are useful as viral transduction enhancers for retroviral gene delivery into cells. Thus, the present invention further relates to the use of peptide amphiphiles as retroviral transduction enhancers in retroviral gene delivery into cells, and to methods for retroviral gene delivery into cells in presence of peptide amphiphiles.
81	Designated WO countries	WDS	AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CV, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IQ, IR, IS, IT, JM, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, MG, MK, MN, MU, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, WS, ZA, ZM, ZW
	Published EP/WO documents	EPWOPN	Original document: WO002024227868A1 Searchable text: WO002024227868A1
43	Date of first publication	EVT	Nov 7, 2024
	Date of the first transfer into DPMAregister	EREGT	Nov 12, 2024
	Date of the (most recent) update in DPMAregister	REGT	Nov 12, 2024 (Show all update days)(Hide all update days) Nov 12, 2024 Date of the first transfer into DPMAregister

Procedural data
No.	Kind of procedure	Legal status	Date of legal/procedural status	Alle Details anzeigen
1	Pre-registration procedure	The application is under preliminary examination	May 2, 2024	Details anzeigen
2	Search procedure	Request for search effectively filed	May 2, 2024	Details anzeigen
3	Procedure relating to PCT application	WO first publication with search report	Nov 7, 2024	Details anzeigen

View procedures Pre-registration procedure (No.: 1)
Criterion	Field	Content Close details
Type of procedure	VART	Pre-registration procedure
Legal/procedural status	VST	The application is under preliminary examination
Date of legal/procedural status	VSTT	May 2, 2024
Date of update of the procedure	REGT	Nov 12, 2024

View procedures Search procedure (No.: 2)
Criterion	Field	Content Close details
Type of procedure	VART	Search procedure
Legal/procedural status	VST	Request for search effectively filed
Date of legal/procedural status	VSTT	May 2, 2024
Third party request		No
Date of receipt	AEGT	May 2, 2024
Date of update of the procedure	REGT	Nov 12, 2024

View procedures Procedure relating to PCT application (No.: 3)
Criterion	Field	Content Close details
Type of procedure	VART	Procedure relating to PCT application
Legal/procedural status	VST	WO first publication with search report
Date of legal/procedural status	VSTT	Nov 7, 2024
Date of update of the procedure	REGT	Nov 12, 2024