Register information Patent

DE file number : 10 2008 045 937.2 (Status: pending/in force, Query started: May 9, 2025)

Please note: This English version is a non-binding translation of the German register excerpt. Only the German version of the register excerpt is legally binding.

Master data
INID	Criterion	Field	Content
	Type of IP right	SART	Patent
	Status	ST	Pending/in force
21	DE file number	DAKZ	10 2008 045 937.2
54	Designation/title	TI	Radiopharmakon aus einem Metallion und einem Markierungsvorläufer und Verwendung des Radiopharmakons
51	IPC main class	ICM (ICMV)	A61K 51/04 (2006.01)
51	IPC secondary class(es)	ICS (ICSV)	C07D 295/04 (2006.01)
22	DE application date	DAT	Sep 4, 2008
43	Date of first publication	OT	Oct 15, 2009
	Date of publication of grant	PET	Jan 26, 2017
71/73	Applicant/owner	INH	SCV - SpezialChemikalienVertrieb GmbH, 55270 Zornheim, DE
72	Inventor	IN	Rösch, Frank, Prof.Dr., 55270 Zornheim, DE; Riß, Patrick, 55122 Mainz, DE; Burchardt, Carsten, 55124 Mainz, DE
74	Representative	VTR	Plate Schweitzer Zounek Patentanwälte, 65203 Wiesbaden, DE
10	Published DE documents	DEPN	Original document: DE102008045937A1 Searchable text: DE102008045937A1 Original document: DE102008045937B4 Searchable text: DE102008045937B4
	Address for service		Patentanwaltskanzlei Plate Schweitzer Zounek Industriepark Kalle-Albert, 65203 Wiesbaden, DE
66 66	Domestic priority	PRN PRD	10 2008 018 634.1 Apr 11, 2008
	Due date	FT FG	Sep 30, 2025 Annual fee for the 18th year Patent fees
	Patent division in charge		43
57	Abstract	AB	Beschrieben ist eine Verbindung aus einem Metallion bzw. Metall, beispielsweise Radiopharmakon aus einem metallischen Radionuklid und einem Markierungsvorläufer, der aus einem bifunktionellen, makrozyklischen Chelator, einem Spacer, einem Linker und mindestens einem Targetingvektor aufgebaut ist. Der Chelator umfasst dabei vorzugsweise einen 9-, 10-, 11-, 12-, 14- oder 16-gliedrigen Polyazamakrozyklus, vorzugsweise weitere komplexbildende Donoren. Der Spacer ist vorzugsweise aus linearen, verzweigten oder heterosubstituierten, gesättigten, ungesättigten oder aromatischen Kohlenwasserstoffen oder aus Zuckern aufgebaut. Targetingvektoren sind bevorzugt proteinogene oder künstliche α-Amino-Carbonsäuren oder umfassen Glucosamin-Einheiten. Die metallischen Radionuklide sind vorzugsweise 2-, 3- oder 4-wertig, wobei die Gallium-Radioisotope ↑65↑Ga, ↑66↑Ga, ↑67↑Ga, ↑68↑Ga, ↑70↑Ga und ↑72↑Ga bevorzugt sind. Das Radiopharmakon eignet sich zur nuklearmedizinischen Diagnostik von Tumoren durch Positronen-Emissions-Tomographie (PET) und durch Single-Photon-Emission-Computed-Tomographie (SPECT). Bei der Endo-Radiotherapie (ERT) wird das Radiopharmakon direkt oder systemisch in das Zielgewebe eingebracht.
56	Citations	CT	US020060182687A1 (US2006/01 82 687 A1) WO002008098056A2 (WO 08/0 98 056 A2) WO002007042504A2 (WO 07/0 42 504 A2)
56	NPL citations	CTNP	G.L. Griffiths et al. "Reagents and Methods for PET Using Bispecific Antibody Pretargeting...", The Journal of Nuclear Medicine 2004, 45(1), 30-39; G.-J. Meyer et al. "68Ga-labelled DOTA-derivatised peptide ligands", Eur. J. Nucl. Med. Mol. Imaging 2004, 31(8), 1097-1104; K.P. Zhernosekov et al. "Processing of Generator-Produced 68Ga for Medical Application", The Journal of Nuclear Medicine 2007, 48(10), 1741-1748; P. Antunes et al."Are radiogallium-labelled DOTA-conjugated somatostatin...", Eur. J. Nucl. Med. Mol. Imaging 2007, 34, 982-993
43	Date of first publication	EVT	Oct 15, 2009
	Number of official communications (office actions)		4
	Number of responses		4
	Date of the first transfer into DPMAregister	EREGT	May 26, 2011
	Date of the (most recent) update in DPMAregister	REGT	May 6, 2025 (Show all update days)(Hide all update days) May 6, 2025 St.36: changed (technical change) Dec 10, 2024 Due date: changed Aug 6, 2024 St.36: changed (technical change) Dec 8, 2023; Dec 19, 2022; Dec 7, 2021; Oct 9, 2021; Dec 4, 2020; Aug 19, 2020; Jul 14, 2020; Dec 6, 2019; Dec 6, 2018; Jan 18, 2018; Dec 14, 2017; Dec 13, 2017; Jan 26, 2017; Jan 5, 2017; Dec 30, 2016; Dec 9, 2016; Nov 25, 2016; Nov 24, 2016; Nov 18, 2016; May 12, 2016; Jan 26, 2016; Dec 3, 2015; Dec 5, 2014; Feb 27, 2014; Feb 23, 2014; Nov 14, 2013; Oct 8, 2013; Feb 12, 2013; Oct 9, 2012; Oct 6, 2012; Aug 25, 2012; Aug 24, 2012; Aug 23, 2012; Aug 22, 2012; Apr 17, 2012; Mar 3, 2012; Mar 2, 2012; Jan 27, 2012; Jan 10, 2012; Dec 28, 2011; Oct 5, 2011; Oct 1, 2011; Sep 21, 2011; Aug 26, 2011; Aug 24, 2011; Aug 12, 2011; Aug 10, 2011; Jul 18, 2011; Jun 3, 2011 Historical data not available for this/these date(s) May 26, 2011 Date of the first transfer into DPMAregister

Procedural data
No.	Kind of procedure	Legal status	Date of legal/procedural status	Publication date	Alle Details anzeigen
1	Pre-registration procedure	The application is under preliminary examination	Sep 4, 2008		Details anzeigen
2	Examination procedure	Request for examination effectively filed	Sep 4, 2008		Details anzeigen
3	Pre-registration procedure	Pre-registration procedure has been concluded	Nov 24, 2008		Details anzeigen
4	Change of classification	Change of IPC main class	Feb 5, 2009	Dec 31, 2009	Details anzeigen
5	Examination procedure	Reply to official communication	Sep 28, 2009		Details anzeigen
6	Publications	Publication of application (Offenlegungsschrift)	Oct 15, 2009	Oct 15, 2009	Details anzeigen
7	Change of classification	Change of IPC main class	Oct 23, 2009	Dec 31, 2009	Details anzeigen
8	Examination procedure	Official communication on examination	Aug 25, 2011		Details anzeigen
9	Examination procedure	Reply to official communication	Feb 27, 2012		Details anzeigen
10	Examination procedure	Official communication on examination	Apr 13, 2012		Details anzeigen
11	Examination procedure	Reply to official communication	Aug 17, 2012		Details anzeigen
12	Examination procedure	Official communication on examination	May 11, 2016		Details anzeigen
13	Examination procedure	Reply to official communication	Nov 16, 2016		Details anzeigen
14	Examination procedure	Decision to grant patent by Examining Section/Patent Division	Nov 24, 2016		Details anzeigen
15	Publications	Patent specification	Jan 26, 2017	Jan 26, 2017	Details anzeigen
16	Examination procedure	Grant of patent has become final	Oct 27, 2017	Jan 18, 2018	Details anzeigen
17	New applicant/owner details	New applicant/owner details	Jul 14, 2020	Aug 20, 2020	Details anzeigen

View procedures Pre-registration procedure (No.: 1)
Criterion	Field	Content Close details
Type of procedure	VART	Pre-registration procedure
Legal/procedural status	VST	The application is under preliminary examination
Date of legal/procedural status	VSTT	Sep 4, 2008

View procedures Examination procedure (No.: 2)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Request for examination effectively filed
Date of legal/procedural status	VSTT	Sep 4, 2008
Third party request		No
Date of receipt	AEGT	Sep 4, 2008

View procedures Pre-registration procedure (No.: 3)
Criterion	Field	Content Close details
Type of procedure	VART	Pre-registration procedure
Legal/procedural status	VST	Pre-registration procedure has been concluded
Date of legal/procedural status	VSTT	Nov 24, 2008

View procedures Change of classification (No.: 4)
INID	Criterion	Field	Content Close details
	Type of procedure	VART	Change of classification
	Legal/procedural status	VST	Change of IPC main class
	Date of legal/procedural status	VSTT	Feb 5, 2009
	Issue number	HN	53
	Year	PJ	2009
	Publication date	VT	Dec 31, 2009
	Type of publication	PART	Bibliographic data
	Part	HT	Part 2
51	IPC main class	ICM (ICMV)	C07D 295/04 (2006.01)
51	Previous IPC main class	ICMF (ICMVF)	C07F 5/00 (2006.01)

View procedures Examination procedure (No.: 5)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Reply to official communication
Date of legal/procedural status	VSTT	Sep 28, 2009

View procedures Publications (No.: 6)
INID	Criterion	Field	Content Close details
	Type of procedure	VART	Publications
	Legal/procedural status	VST	Publication of application (Offenlegungsschrift)
	Date of legal/procedural status	VSTT	Oct 15, 2009
	Issue number	HN	42
	Year	PJ	2009
	Publication date	VT	Oct 15, 2009
	Type of publication	PART	Documents
	Part	HT	Part 2
10	Published DE documents	DEPN	Original document: DE102008045937A1 Searchable text: DE102008045937A1

View procedures Change of classification (No.: 7)
INID	Criterion	Field	Content Close details
	Type of procedure	VART	Change of classification
	Legal/procedural status	VST	Change of IPC main class
	Date of legal/procedural status	VSTT	Oct 23, 2009
	Issue number	HN	53
	Year	PJ	2009
	Publication date	VT	Dec 31, 2009
	Type of publication	PART	Bibliographic data
	Part	HT	Part 2
51	IPC main class	ICM (ICMV)	A61K 51/04 (2006.01)
51	Previous IPC main class	ICMF (ICMVF)	C07D 295/04 (2006.01)

View procedures Examination procedure (No.: 8)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Official communication on examination
Date of legal/procedural status	VSTT	Aug 25, 2011

View procedures Examination procedure (No.: 9)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Reply to official communication
Date of legal/procedural status	VSTT	Feb 27, 2012

View procedures Examination procedure (No.: 10)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Official communication on examination
Date of legal/procedural status	VSTT	Apr 13, 2012

View procedures Examination procedure (No.: 11)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Reply to official communication
Date of legal/procedural status	VSTT	Aug 17, 2012

View procedures Examination procedure (No.: 12)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Official communication on examination
Date of legal/procedural status	VSTT	May 11, 2016

View procedures Examination procedure (No.: 13)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Reply to official communication
Date of legal/procedural status	VSTT	Nov 16, 2016

View procedures Examination procedure (No.: 14)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Decision to grant patent by Examining Section/Patent Division
Date of legal/procedural status	VSTT	Nov 24, 2016

View procedures Publications (No.: 15)
INID	Criterion	Field	Content Close details
	Type of procedure	VART	Publications
	Legal/procedural status	VST	Patent specification
	Date of legal/procedural status	VSTT	Jan 26, 2017
	Issue number	HN	4
	Year	PJ	2017
	Publication date	VT	Jan 26, 2017
	Type of publication	PART	Documents
	Part	HT	Part 3
10	Published DE documents	DEPN	Original document: DE102008045937B4 Searchable text: DE102008045937B4

View procedures Examination procedure (No.: 16)
Criterion	Field	Content Close details
Type of procedure	VART	Examination procedure
Legal/procedural status	VST	Grant of patent has become final
Date of legal/procedural status	VSTT	Oct 27, 2017
Issue number	HN	3
Year	PJ	2018
Publication date	VT	Jan 18, 2018
Type of publication	PART	Bibliographic data
Part	HT	Part 3

View procedures New applicant/owner details (No.: 17)
INID	Criterion	Field	Content Close details
	Type of procedure	VART	New applicant/owner details
	Legal/procedural status	VST	New applicant/owner details
	Date of legal/procedural status	VSTT	Jul 14, 2020
	Issue number	HN	34
	Year	PJ	2020
	Publication date	VT	Aug 20, 2020
	Type of publication	PART	Bibliographic data
	Part	HT	Part 3
71/73	Applicant/owner	INH	SCV - SpezialChemikalienVertrieb GmbH, 55270 Zornheim, DE
71/73	Previous applicant/owner	INHF	Johannes-Gutenberg-Universität Mainz, 55122 Mainz, DE
	Date of update of the procedure	REGT	Aug 19, 2020